POWERSTROKE-P0301 serious Power Stroke ›

Cylinder 1 Misfire Detected

The POWERSTROKE-P0301 (Power Stroke) diesel fault code means: Cylinder 1 Misfire Detected. This is a serious severity code.

My Garage →
Keep driving?
Short distances only
DIY difficulty
advanced
Estimated cost
$500-$9,000 (piston/liner damage is the worst case)
Mobile mechanic network · I-5 corridor pilot

Down with a Power Stroke fault on the road?

Get connected with a verified mobile diesel mechanic near you. Verified diesel & reefer techs, launching on the freight corridor.

Find a mobile mechanic →
Built for Diesel — Not a Car Reader
ANCEL HD7000 Heavy-Duty Diesel Scanner

A $30 car code reader can't do diesel. The HD7000 reads full-system codes and does parked DPF regen, idle/speed-limit, and service resets from the cab — on everything from a 6.7 Cummins/Power Stroke/Duramax pickup to Class-8 trucks (Detroit, Paccar, CAT, Volvo, Mack, International).

Check Price on Amazon

Affiliate link -- we earn a commission at no extra cost to you.

Lower-Cost Diesel Option
FOXWELL HD301 Diesel Truck Scanner

Full-system 6/9/16-pin diesel scan tool for Cummins, Paccar, CAT, Detroit and more — plug-and-play, no subscription. A cheaper way to read heavy-duty codes a basic OBD2 scanner skips entirely.

Check Price on Amazon

Affiliate link -- we earn a commission at no extra cost to you.

Common Symptoms

  • Cylinder 1 misfire
  • Rough running
  • CEL flashing possible
  • Vibration at idle

Probable Causes (Ranked by Likelihood)

  • Cracked piston (6.4L has piston-cracking issues on deleted / over-fueled trucks) Very Likely
  • Failed injector (6.4L piezo injectors are expensive) Likely
  • Low compression from broken ring or melted piston Possible
  • Stuck open injector flooding the cylinder Possible

Step-by-Step Diagnostic Procedure

  1. Perform relative compression test via scan tool.

  2. If compression is low on one cylinder, borescope through injector hole or glow plug port.

  3. Check injector balance rates / CCT data.

  4. Replace injectors as a set on 6.4L if multiple cylinders show fueling issues.

Frequently Asked Questions

What is P0301 on a 6.4L Power Stroke?

P0301 on a 6.4L Power Stroke (2008-2010) indicates: Cylinder 1 Misfire Detected. This is a known diagnostic trouble code on this engine family and typically points to the causes listed above.

Can I drive with P0301 on my Power Stroke?

Only drive short distances to get to a repair facility. Continued operation may cause further damage.

How much does it cost to fix P0301?

Repair cost is typically $500-$9,000 (piston/liner damage is the worst case) depending on the underlying cause and whether you DIY or use a shop. Diagnostic time alone runs $100-$180 at most independent diesel shops.

P0301 on Other Platforms

The same code ID appears across other engines, vehicles, and equipment. Diagnostic flow varies by platform — see the matching breakdown:

Explore More